Randox Laboratories, Kearneysville, W Va, offers a reagent for the detection of small, dense low-density lipoprotein cholesterol particles (sd-LDL). The liquid, ready-to-use product has a measuring range of 0.189–22.2 mmol/L, comfortably detecting levels outside of the healthy limit of 4.9 mmol/L. LDLs transport essential triglycerides and cholesterol to the body’s tissues, but they can vary in size as a result of an individual’s genetic makeup and dietary lipid intake, and their atherogenc potential also varies according to their size. Smaller particles such as sd-LDL more readily permeate the inner arterial wall and are more susceptible to oxidation, resulting in the build-up of fatty plaques within the arteries. Measurement of sd-LDL enables clinicians to obtain a more comprehensive picture of lipid risk factors and tailor treatment accordingly. Randox’s  reagent utilizes the LDL-Ex Seiken method, which moves away from time-consuming ultracentrifugation- and electrophoresis-based methods. Used on most automated biochemistry analyzers, the reagent completes particle detection within 10 minutes. It is stable to expiry when stored at 2-8°C. For research use only. For more information, visit Randox at AACC booth 1335.