For laboratory professionals who prefer to pour their own gels, the SureCast gel handcast system from Thermo Fisher Scientific, Waltham, Mass, was developed to save time, money, and precious samples. The system features ultradurable glass plates, which are more than three times thicker and up to 20 times more durable than currently available glass plates. A single-motion, load-and-lock system also creates a securely sealed assembly for confident protein gel casting. For use with the system, Invitrogen SureCast stacking buffer and Invitrogen SureCast resolving buffer are pouches of dry-blend powder, each sufficient to make 500 mL of stacking gel buffer or 500 mL of resolving gel buffer for handcasting polyacrylamide gels. For research use only. For more information, visit Thermo Fisher Scientific.